Validated automatic speech biomarkers in primary progressive aphasia
نویسندگان
چکیده
منابع مشابه
Automatic speech recognition in the diagnosis of primary progressive aphasia
Narrative speech can provide a valuable source of information about an individual’s linguistic abilities across lexical, syntactic, and pragmatic levels. However, analysis of narrative speech is typically done by hand, and is therefore extremely time-consuming. Use of automatic speech recognition (ASR) software could make this type of analysis more efficient and widely available. In this paper,...
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BACKGROUND Primary progressive aphasia (PPA) is a neurodegenerative disorder with no effective pharmacological treatment. Cognition-based interventions are adequate alternatives, but their benefit has not been thoroughly explored. Our aim was to study the effect of speech and language therapy (SLT) on naming ability in PPA. METHODS An open parallel prospective longitudinal study involving two...
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We describe ten patients with a clinical diagnosis of primary progressive aphasia (PPA) (pathologically confirmed in three cases) who developed abnormal laughter-like vocalisations in the context of progressive speech output impairment leading to mutism. Failure of speech output was accompanied by increasing frequency of the abnormal vocalisations until ultimately they constituted the patient's...
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Primary progressive aphasia is a clinical syndrome defined by progressive deficits isolated to speech and/or language, and can be classified into non-fluent, semantic and logopenic variants based on motor speech, linguistic and cognitive features. The connected speech of patients with primary progressive aphasia has often been dichotomized simply as 'fluent' or 'non-fluent', however fluency is ...
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A 65-year-old man presented with word-finding difficulty and gait disturbance. His speech was nonfluent with word retrieval impairment and difficulties with sentence repetition. Other cognitive domains were intact initially. He developed asymmetrical bradykinesia, rigidity and a rest tremor. Over the following 8 years, his speech production impairment slowly deteriorated with the development of...
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ژورنال
عنوان ژورنال: Annals of Clinical and Translational Neurology
سال: 2018
ISSN: 2328-9503
DOI: 10.1002/acn3.653